Pathguide: the pathway resource list
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Full Record: STRING  
Short NameSTRING
Full NameSearch Tool for the Retrieval of Interacting Genes/Proteins
Last ObservedFebruary 15th, 2017
DescriptionSTRING makes available precomputed gene neighborhood, gene fusion, phylogenetic profile, co-expression, and co-mentioned in PubMed abstract based protein-protein functional associations combined with collected experimental and database evidence information for over 375 genomes in a very graphical and user friendly manner.

This database is free to use online and to download some flatfiles, but in order to download the full database (or some other flatfiles, specifically for commercial users) a license is required.
Sample Data URL
Data SourceSecondary
AvailabilityLicense purchase required
PubMed ArticlesSTRING: a web-server to retrieve and display the repeatedly occurring neighbourhood of a gene.
Snel B, Lehmann G, Bork P, Huynen MA.
Nucleic Acids Res. 2000 Sep 15;28(18):3442-4.

STRING: a database of predicted functional associations between proteins.
von Mering C, Huynen M, Jaeggi D, Schmidt S, Bork P, Snel B.
Nucleic Acids Res. 2003 Jan 1;31(1):258-61.

STRING: known and predicted protein-protein associations, integrated and transferred across organisms
von Mering C, Jensen LJ, Snel B, Hooper SD, Krupp M, Foglierini M, Jouffre N, Huynen MA, Bork P.
Nucleic Acids Res. 2005 Jan 1;33(Database issue):D433-7.

STRING 7--recent developments in the integration and prediction of protein interactions.
von Mering C, Jensen LJ, Kuhn M, Chaffron S, Doerks T, Kruger B, Snel B, Bork P.
Nucleic Acids Res. 2007 Jan;35(Database issue):D358-62. Epub 2006 Nov 10.

STRING 8--a global view on proteins and their functional interactions in 630 organisms.
Jensen LJ, Kuhn M, Stark M, Chaffron S, Creevey C, Muller J, Doerks T, Julien P, Roth A, Simonovic M, Bork P, Mering CV.
Nucleic Acids Res. 2008 Oct 21

The STRING database in 2011: functional interaction networks of proteins, globally integrated and scored.
Szklarczyk D, Franceschini A, Kuhn M, Simonovic M, Roth A, Minguez P, Doerks T, Stark M, Muller J, Bork P, Jensen LJ, von Mering C
Nucleic Acids Res. 2011 Jan;39(Database issue):D561-8.

STRING v9.1: protein-protein interaction networks, with increased coverage and integration.
Franceschini A, Szklarczyk D, Frankild S, Kuhn M, Simonovic M, Roth A, Lin J, Minguez P, Bork P, von Mering C, Jensen LJ
Nucleic Acids Res. 2013 Jan;41(Database issue):D808-15.

STRING v10: protein-protein interaction networks, integrated over the tree of life.
Szklarczyk D, Franceschini A, Wyder S, Forslund K, Heller D, Huerta-Cepas J, Simonovic M, Roth A, Santos A, Tsafou KP, Kuhn M, Bork P, Jensen LJ, von Mering C.
Nucleic Acids Res. 2015 Jan;43(Database issue):D447-52.

The STRING database in 2017: quality-controlled protein-protein association networks, made broadly accessible.
Szklarczyk D, Morris JH, Cook H, Kuhn M, Wyder S, Simonovic M, Santos A, Doncheva NT, Roth A, Bork P, Jensen LJ, von Mering C.
Nucleic Acids Res. 2017 Jan 4;45(D1):D362-D368.

Types of DataProtein-Protein Interactions
Types of ToolsText mining, Pathway discovery tools, Interaction or functional association prediction
Genes / Proteins: 9,643,763
Interactions / Reactions: 1,380,838,440
Last Content Update: May 14th, 2017
Major OrganismsEscherichia coli, Homo sapiens, Saccharomyces cerevisiae
Relative Popularity1100
Homepage Uptime StatisticsWebsite tracker - uptime monitoring service
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"Pathguide: the pathway resource list" is maintained by Gary Bader1.
The website was originally created by Michael Cary 2 and was significantly updated and redesigned by Vuk Pavlovic1.
Thanks to Emek Demir for the Pathguide name.

1. Bader Lab
2. Sander Group

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