|A Knowledge Resource for Innate Immunity Interactions and Pathways|
|February 8th, 2017|
|InnateDB has been developed to facilitate systems level investigations of the innate immune response in human and mice. Its goal is to provide a manually-curated knowledgebase of the genes, proteins, and particularly, the interactions and signaling responses involved in the mammalian innate immune response. InnateDB incorporates information of the whole human and mouse interactomes by integrating interaction and pathway information from several of the major publicly available databases but aims to capture an improved coverage of the innate immunity interactome through manual curation.|
|Free to all users|
|InnateDB: facilitating systems-level analyses of the mammalian innate immune response.|
Lynn DJ, Winsor GL, Chan C, Richard N, Laird MR, Barsky A, Gardy JL, Roche FM, Chan TH, Shah N, Lo R, Naseer M, Que J, Yau M, Acab M, Tulpan D, Whiteside MD, Chikatamarla A, Mah B, Munzner T, Hokamp K, Hancock RE, Brinkman FS.
Mol Syst Biol. 2008;4:218.
InnateDB: systems biology of innate immunity and beyond--recent updates and continuing curation.
Breuer K, Foroushani AK, Laird MR, Chen C, Sribnaia A, Lo R, Winsor GL, Hancock RE, Brinkman FS, Lynn DJ
Nucleic Acids Res. 2013 Jan;41(Database issue):D1228-33.
|Protein-Protein Interactions, Signaling Pathways|
|Text mining, Pathway diagram tools, Interaction or functional association prediction|
|Genes / Proteins: ||25,110|
|Interactions / Reactions: ||829,924|
|Experiments / PubMed IDs: ||35,747|
|Last Content Update: ||June 20th, 2017|
|Bos taurus, Homo sapiens, Mus musculus|