Pathguide: the pathway resource list
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Full Record: InnateDB  
Short NameInnateDB
Full NameA Knowledge Resource for Innate Immunity Interactions and Pathways
Last ObservedFebruary 8th, 2017
DescriptionInnateDB has been developed to facilitate systems level investigations of the innate immune response in human and mice. Its goal is to provide a manually-curated knowledgebase of the genes, proteins, and particularly, the interactions and signaling responses involved in the mammalian innate immune response. InnateDB incorporates information of the whole human and mouse interactomes by integrating interaction and pathway information from several of the major publicly available databases but aims to capture an improved coverage of the innate immunity interactome through manual curation.
Sample Data URL 
Data SourcePrimary
AvailabilityFree to all users
PubMed ArticlesInnateDB: facilitating systems-level analyses of the mammalian innate immune response.
Lynn DJ, Winsor GL, Chan C, Richard N, Laird MR, Barsky A, Gardy JL, Roche FM, Chan TH, Shah N, Lo R, Naseer M, Que J, Yau M, Acab M, Tulpan D, Whiteside MD, Chikatamarla A, Mah B, Munzner T, Hokamp K, Hancock RE, Brinkman FS.
Mol Syst Biol. 2008;4:218.

InnateDB: systems biology of innate immunity and beyond--recent updates and continuing curation.
Breuer K, Foroushani AK, Laird MR, Chen C, Sribnaia A, Lo R, Winsor GL, Hancock RE, Brinkman FS, Lynn DJ
Nucleic Acids Res. 2013 Jan;41(Database issue):D1228-33.

Types of DataProtein-Protein Interactions, Signaling Pathways
Types of ToolsText mining, Pathway diagram tools, Interaction or functional association prediction
Genes / Proteins: 25,110
Interactions / Reactions: 829,924
Experiments / PubMed IDs: 35,747
Last Content Update: June 20th, 2017
Major OrganismsBos taurus, Homo sapiens, Mus musculus
Relative Popularity78
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"Pathguide: the pathway resource list" is maintained by Gary Bader1.
The website was originally created by Michael Cary 2 and was significantly updated and redesigned by Vuk Pavlovic1.
Thanks to Emek Demir for the Pathguide name.

1. Bader Lab
2. Sander Group

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