Pathguide: the pathway resource list
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Full Record: KEGG  
Short NameKEGG
Full NameKyoto Encyclopedia of Genes and Genomes
Last ObservedFebruary 22nd, 2017
DescriptionA large database of metabolic pathways from multiple organisms. Reference pathways are available that describe a general pathway, which is then projected onto a genome based on the presence of pathway enzymes in that genome. KEGG is actually composed of a number of databases: PATHWAY, GENES, LIGAND, DISEASE, and DRUG. Some information on molecular complexes and signaling pathways is present, although mainly in diagram form.
Sample Data URL 
Data SourcePrimary
AvailabilityFree to academic users
PubMed ArticlesA database for post-genome analysis.
Kanehisa M.
Trends Genet. 1997 Sep;13(9):375-6.

KEGG: Kyoto Encyclopedia of Genes and Genomes.
Ogata H, Goto S, Sato K, Fujibuchi W, Bono H, Kanehisa M.
Nucleic Acids Res. 1999 Jan 1;27(1):29-34

KEGG: kyoto encyclopedia of genes and genomes.
Kanehisa M, Goto S.
Nucleic Acids Res. 2000 Jan 1;28(1):27-30

The Kyoto encyclopedia of genes and genomes--KEGG.
Wixon J, Kell D.
Yeast. 2000 Apr;17(1):48-55

The KEGG databases at GenomeNet.
Kanehisa M, Goto S, Kawashima S, Nakaya A.
Nucleic Acids Res. 2002 Jan 1;30(1):42-6

The KEGG database.
Kanehisa M.
Novartis Found Symp. 2002;247:91-101; discussion 101-3, 119-28, 244-52

The KEGG resource for deciphering the genome.
Kanehisa M, Goto S, Kawashima S, Okuno Y, Hattori M.
Nucleic Acids Res. 2004 Jan 1;32(Database issue):D277-80

From genomics to chemical genomics: new developments in KEGG
Kanehisa M, Goto S, Hattori M, Aoki-Kinoshita KF, Itoh M, Kawashima S, Katayama T, Araki M, Hirakawa M.
Nucleic Acids Res. 2006 Jan 1;34(Database issue):D354-7

Gene annotation and pathway mapping in KEGG
Aoki-Kinoshita KF, Kanehisa M.
Methods Mol Biol. 2007;396:71-91

KEGG for linking genomes to life and the environment.
Kanehisa M, Araki M, Goto S, Hattori M, Hirakawa M, Itoh M, Katayama T, Kawashima S, Okuda S, Tokimatsu T, Yamanishi Y.
Nucleic Acids Res. 2008 Jan;36(Database issue):D480-4.

KEGG for representation and analysis of molecular networks involving diseases and drugs.
Kanehisa M, Goto S, Furumichi M, Tanabe M, Hirakawa M.
Nucleic Acids Res. 2010;38 (Database issue):D355-D360

KEGG for integration and interpretation of large-scale molecular data sets.
Kanehisa M, Goto S, Sato Y, Furumichi M, Tanabe M
Nucleic Acids Res. 2012 Jan;40(Database issue):D109-14.

Using the KEGG database resource.
Tanabe M, Kanehisa M
Curr Protoc Bioinformatics. 2012 Jun;Chapter 1:Unit1.12.

Data, information, knowledge and principle: back to metabolism in KEGG.
Kanehisa M, Goto S, Sato Y, Kawashima M, Furumichi M, Tanabe M.
Nucleic Acids Res. 2014 Jan;42(Database issue):D199-205.

KEGG as a reference resource for gene and protein annotation.
Kanehisa M, Sato Y, Kawashima M, Furumichi M, Tanabe M.
Nucleic Acids Res. 2016 Jan 4;44(D1):D457-62.

KEGG: new perspectives on genomes, pathways, diseases and drugs.
Kanehisa M, Furumichi M, Tanabe M, Sato Y, Morishima K.
Nucleic Acids Res. 2017 Jan 4;45(D1):D353-D361.

Types of DataMetabolic Pathways, Pathway Diagrams
Types of Tools
Small Molecules: 18,105
Genes / Proteins: 23,522,122
Interactions / Reactions: 10,652
Pathways: 527,925
Last Content Update: August 1st, 2017
Major Organisms
Relative Popularity2490
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"Pathguide: the pathway resource list" is maintained by Gary Bader1.
The website was originally created by Michael Cary 2 and was significantly updated and redesigned by Vuk Pavlovic1.
Thanks to Emek Demir for the Pathguide name.

1. Bader Lab
2. Sander Group

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