|Human Protein Reference Database |
|February 8th, 2017|
|HPRD is a database of human proteins, but also contains a significant amount of protein-protein interactions. Information about the domain and region of interaction, if available, is present as well as the type of experiment done to detect the interaction. Expression, domain architecture and post-translational modifications are also curated for each protein. A number of curated pathways created from the interaction data are available as images. |
|Free to academic users|
|Development of human protein reference database as an initial platform for approaching systems biology in humans.|
Peri S, Navarro JD, Amanchy R, Kristiansen TZ, Jonnalagadda CK, Surendranath V, Niranjan V, Muthusamy B, Gandhi TK, Gronborg M, Ibarrola N, Deshpande N, Shanker K, Shivashankar HN, Rashmi BP, Ramya MA, Zhao Z, Chandrika KN, Padma N, Harsha HC, Yatish AJ, Kavitha MP, Menezes M, Choudhury DR, Suresh S, Ghosh N, Saravana R, Chandran S, Krishna S, Joy M, Anand SK, Madavan V, Joseph A, Wong GW, Schiemann WP, Constantinescu SN, Huang L, Khosravi-Far R, Steen H, Tewari M, Ghaffari S, Blobe GC, Dang CV, Garcia JG, Pevsner J, Jensen ON, Roepstorff P, Deshpande KS, Chinnaiyan AM, Hamosh A, Chakravarti A, Pandey A.
Genome Res. 2003 Oct;13(10):2363-71
Human protein reference database as a discovery resource for proteomics.
Peri S, Navarro JD, Kristiansen TZ, Amanchy R, Surendranath V, Muthusamy B, Gandhi TK, Chandrika KN, Deshpande N, Suresh S, Rashmi BP, Shanker K, Padma N, Niranjan V, Harsha HC, Talreja N, Vrushabendra BM, Ramya MA, Yatish AJ, Joy M, Shivashankar HN, Kavitha MP, Menezes M, Choudhury DR, Ghosh N, Saravana R, Chandran S, Mohan S, Jonnalagadda CK, Prasad CK, Kumar-Sinha C, Deshpande KS, Pandey A.
Nucleic Acids Res. 2004 Jan 1;32(Database issue):D497-501
Human protein reference database--2006 update.
Mishra GR, Suresh M, Kumaran K, Kannabiran N, Suresh S, Bala P, Shivakumar K, Anuradha N, Reddy R, Raghavan TM, Menon S, Hanumanthu G, Gupta M, Upendran S, Gupta S, Mahesh M, Jacob B, Mathew P, Chatterjee P, Arun KS, Sharma S, Chandrika KN, Deshpande N, Palvankar K, Raghavnath R, Krishnakanth R, Karathia H, Rekha B, Nayak R, Vishnupriya G, Kumar HG, Nagini M, Kumar GS, Jose R, Deepthi P, Mohan SS, Gandhi TK, Harsha HC, Deshpande KS, Sarker M, Prasad TS, Pandey A
Nucleic Acids Res. 2006 Jan 1;34(Database issue):D411-4
Human Protein Reference Database--2009 update.
Prasad TS, Goel R, Kandasamy K, Keerthikumar S, Kumar S, Mathivanan S, Telikicherla D, Raju R, Shafreen B, Venugopal A, Balakrishnan L, Marimuthu A, Banerjee S, Somanathan DS, Sebastian A, Rani S, Ray S, Kishore CJ, Kanth S, Ahmed M, Kashyap MK, Mohmood R, Ramachandra YL, Krishna V, Rahiman BA, Mohan S, Ranganathan P, Ramabadran S, Chaerkady R, Pandey A.
Nucleic Acids Res. 2008 Nov 6.
Human Protein Reference Database and Human Proteinpedia as discovery tools for systems biology.
Prasad TS, Kandasamy K, Pandey A
Methods Mol Biol. 2009;577:67-79.
Human protein reference database and human proteinpedia as discovery resources for molecular biotechnology.
Goel R, Muthusamy B, Pandey A, Prasad TS
Mol Biotechnol. 2011 May;48(1):87-95.
Human Protein Reference Database and Human Proteinpedia as resources for phosphoproteome analysis.
Goel R, Harsha HC, Pandey A, Prasad TS
Mol Biosyst. 2012 Feb;8(2):453-63.
|Protein-Protein Interactions, Pathway Diagrams|
|Genes / Proteins: ||30,047|
|Interactions / Reactions: ||41,327|
|Experiments / PubMed IDs: ||453,521|
|Last Content Update: ||April 13th, 2010|